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Symbol Name ID |
Ltb
lymphotoxin B MGI:104796 |
| Darker colors indicate more annotations |
| Mouse Phenotypes | colitis |
spleen hyperplasia |
abnormal class switch recombination |
absent germinal center B cells |
decreased marginal zone B cell number |
increased lymphocyte cell number |
increased leukocyte cell number |
abnormal spleen morphology |
abnormal spleen red pulp morphology |
intermingled spleen red and white pulp |
abnormal spleen white pulp morphology |
abnormal spleen B cell follicle morphology |
decreased spleen B cell follicle number |
abnormal spleen follicular dendritic cell network |
abnormal spleen germinal center morphology |
absent spleen germinal center |
decreased spleen germinal center number |
decreased spleen germinal center size |
abnormal spleen marginal zone morphology |
absent spleen marginal zone |
decreased spleen white pulp amount |
decreased IgA level |
decreased IgG1 level |
decreased IgG2a level |
decreased IgG level |
increased IgM level |
absent follicular dendritic cells |
small Peyer's patches |
absent Peyer's patches |
abnormal mesenteric lymph node morphology |
absent mesenteric lymph nodes |
absent axillary lymph nodes |
absent brachial lymph nodes |
absent cervical lymph nodes |
absent inguinal lymph nodes |
absent popliteal lymph nodes |
absent peripheral lymph nodes |
absent lymph nodes |
abnormal adaptive immunity |
abnormal humoral immune response |
increased susceptibility to bacterial infection |
increased susceptibility to bacterial infection induced morbidity/mortality |
increased susceptibility to parasitic infection |
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| Availability | Mouse Genotype | |||||||||||||||||||||||||||||||||||||||||||
| Ltb/Tnf/Ltatm1Dvk/Ltb/Tnf/Ltatm1Dvk | ||||||||||||||||||||||||||||||||||||||||||||
| Ltb/Tnftm1.1Dvk/Ltb/Tnftm1.1Dvk | ||||||||||||||||||||||||||||||||||||||||||||
| Ltbtm1Flv/Ltbtm1Flv | ||||||||||||||||||||||||||||||||||||||||||||
| Ltbtm1Kpf/Ltbtm1Kpf | ||||||||||||||||||||||||||||||||||||||||||||
| Ltbtm1Krn/Ltbtm1Krn | ||||||||||||||||||||||||||||||||||||||||||||
| Cd19tm1(cre)Cgn/Cd19+ Ltbtm1Avt/Ltbtm1Avt (conditional) |
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| Cd19tm1(cre)Cgn/Cd19+ Ltbtm1Avt/Ltbtm1Avt Tg(Lck-cre)1Jtak/? (conditional) |
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 04/30/2024 MGI 6.23 |
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